Vlad Sandulache, M.D. Ph.D.
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Vlad Sandulache, M.D. Ph.D.
Associate Professor; Vice Chair - Research; Chief of Service at MED VAMC
Positions
- Associate Professor; Vice Chair - Research; Chief of Service at MED VAMC
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Otolaryngology-Head & Neck Surgery
7m视频
Houston, Texas United States
- Core Faculty
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Center for Translational Research on Inflammatory Diseases (CTRID)
Michael E. DeBakey VA Medical Center
7m视频
Houston, Texas United States
- Member
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Dan L Duncan Comprehensive Cancer Center
7m视频
Houston, Texas United States
Addresses
- Jamail Specialty Care Center (Clinic)
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1977 Butler Blvd.
Suite E5.200
Houston, TX 77030
United States
Phone: (713) 798-5900
Education
- MD-PhD from University of Pittsburgh School of Medicine
- 05/2008 - Pittsburgh, United States
- Residency at 7m视频, Department of Otolaryngology Head and Neck Surgery
- 06/2015 - Houston, Texas United States
- Clinical Fellowship at University of Texas MD Anderson Cancer Center, Department of Head and Neck Surgery
- 06/2016 - Houston, Texas United States
Certifications
- Diplomate
- American Board of Otolaryngology-Head and Neck Surgery
Honors & Awards
- Fellow
- American College of Surgeons
Professional Interests
- Laryngeal and pharyngeal cancer
- Thyroid cancer
- Salivary gland neoplasm
- Melanoma
- Advanced skin cancer
Professional Statement
Vlad C. Sandulache MD, PhD is a board certified otolaryngologist specializing in Head and Neck Surgical Oncology. Dr. Sandulache earned his MD and PhD from the University of Pittsburgh, and completed his residency in Otolaryngology Head and Neck Surgery at 7m视频. Following residency, Dr. Sandulache completed a clinical fellowship in the Department of Head and Neck Surgery at The University of Texas MD Anderson Cancer Center where he received advanced training in minimally invasive surgical techniques for pharyngeal and laryngeal malignancies including transoral robotic surgery (TORS) and transoral laser surgery.Dr. Sandulache utilizes a multidisciplinary approach to the management of patients with head and neck cancer with active participation in both surgical and non-surgical clinical trials. His primary clinical expertise is in the management of early and advanced stage oral cavity, oropharyngeal and laryngeal cancer as well as salivary gland neoplasms.
Dr. Sandulache maintains an active basic science and clinical research program focused on elucidating the link between cancer metabolism and treatment effectiveness. The goal of this research program is to better understand environmental and intrinsic drivers of chemo-radiation and immune checkpoint inhibitor response to advance risk-stratification and precision oncology approaches for head and neck cancer.
Websites
Selected Publications
- Yu W, Chen Y, Dubrulle J, Stossi F, Putluri V, Sreekumar A, Putluri N, Baluya D, Lai SY, Sandulache VC. "." Sci Rep. 2018 Mar 9;8(1):4306. Pubmed PMID:
- Sandulache VC, Michikawa C, Kataria P, Gleber-Netto FO, Bell D, Trivedi S, Rao X, Wang J, Zhao M, Jasser S, Myers JN, Pickering CR. "." Clin Cancer Res. 2018 Apr 1;24(7):1727-1733. Pubmed PMID:
- Krupar R, Hautmann MG, Pathak RR, Varier I, McLaren C, Gaag D, Hellerbrand C, Evert M, Laban S, Idel C, Sandulache V, Perner S, Bosserhoff AK, Sikora AG. "." Am J Pathol. 2018 Jan;188(1):72-83. Pubmed PMID:
- Wangjie Yu, Yunyun Chen, Nagireddy Putluri, Cristian Coarfa, Matthew Robertson, Vasanta Putluri, Fabio Stossi, Julien Dubrulle, Michael Mancini, Jonathan Pang, Trung Nguyen, Dodge Baluya, Jeffrey Myers, Stephen Lai, Vlad Sandulache "Acquisition of Cisplatin Resistance Shifts Head and Neck Squamous Cell Carcinoma Metabolism toward Neutralization of Oxidative Stress." Cancer (Basel). 2020 Jun 24;12(6):1670.
- Mitchell Frederick, Heath D Skinner, Sawad A Kazi, Andrew G Sikora, Vlad C Sandulache "High expression of oxidative phosphorylation genes predicts improved survival in squamous cell carcinomas of the head and neck and lung." 2020 Apr 14;10(1):6380.
- J O Kemnade, H Elhalawani, P Castro, J Yu, S Lai, M Ittmann, A S R Mohamed, S Y Lai, C D Fuller, A G Sikora, V C Sandulache "CD8 infiltration is associated with disease control and tobacco exposure in intermediate-risk oropharyngeal cancer." 2020 Jan 14;10(1):243.
- V Sandulache, Y Lei, L Heasley, M Chang, C Amos, E Sturgis, E Graboyes, E Chiao, N Rogus-Pulia, J Lewis, A Madabhushi, M Frederick, A Sabichi, M Ittmann, W Yarbrough, C Chung, R Ferrarotto, W Mai, H Skinner, U Duvvuri, P Gerngross, A Sikora "Innovations in risk-stratification and treatment of Veterans with oropharynx cancer; roadmap of the 2019 Field Based Meeting." 2020 Mar;102:104440.
- Osman AA, Arslan E, Bartels M, Michikawa C, Lindemann A, Tomczak K, Yu W, Sandulache V, Ma W, Shen L, Wang J, Singh AK, Frederick MJ, Spencer ND, Kovacs J, Heffernan T, Symmans WF, Rai K, Myers JN. "." Clin Cancer Res. 2023 Jan 23; Pubmed PMID:
- Liu Y, Kramer JR, Sandulache VC, Yu R, Li G, Chen L, Yusuf ZI, Shi Y, Pyarajan S, Tsavachidis S, Jiao L, Mierzwa ML, Chiao E, Mowery YM, Shuman A, Shete S, Sikora AG, White DL. "." Cancer Res. 2023 Feb 3;83(3):386-397. Pubmed PMID:
Memberships
- American Head and Neck Society
- Member (06/2015)
Funding
- The Houston Center for Acquired Resistance Research (H-CARR) - #U54CA274321 (09/20/2022 - 08/31/2027) Grant funding from National Cancer Institute
- Leveraging Hyperpolarized MRI for Precision Oncology Approaches in Head and Neck Cancer - #R01CA280980 (09/01/2022 - 08/31/2027) Grant funding from National Cancer Institute
- Overcoming cisplatin resistance by targeting fatty acid metabolism - #R03DE028858 (08/01/2019 - 07/31/2021) Grant funding from National Institute of Dental and Craniofacial Research
- Determining the impact of ancestry on oropharyngeal cancer biology and treatment response. - #1R21DE032344-01 (07/01/2023 - 06/30/2025) Grant funding from National Institute of Dental and Craniofacial Research
- Profiling tobacco exposure effects on oropharyngeal cancer immunity - #RSG 21-182-01-CDP (01/01/2022 - 12/31/2026) Grant funding from American Cancer Society
Languages
Romanian
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