Positions
- Assistant Professor
-
Medicine-Cardiovascular Sciences
7m视频
Houston, TX US
- Consultant
-
Indus Instruments
Houston, Texas United States
Education
- Postdoctoral Fellowship at 7m视频
- 03/2001 - Houston, Texas United States
- PhD from Texas A&M University
- 12/1996 - College Station, Texas United States
- MS from University of Akron
- 05/1991 - Akron, Ohio United States
- BE from Osmania University
- 08/1985 - Hyderabad, Telangana India
Honors & Awards
- NIH Research Career Development Award
- 01/2005 - 01/2010
Professional Statement
Dr. Reddy鈥檚 research interests include evaluation of cardiac and vascular mechanics in senescent, disease, transgenic, and surgical models of mice. Some of the rodent models he studies include atherosclerosis, dwarf, myocardial infarction/remodeling, pressure overload, hypertension, absent vascular tone, and absent steroid receptor coactivator-1, with the main goal being to translate what is learned in mice to humans for early detection and screening.Using noninvasive methods, such as pulsed Doppler Flow Velocity measurements as well as imaging methods, animals are phenotyped as abnormalities develop and progress, and their cardiovascular system is monitored as it adapts and compensates for the deterioration of function or for missing or over-expressed proteins. The main goal is to translate what is learned in mice to humans for detection and screening of cardiovascular diseases at an early stage when potential therapies can be most effective at preventing disease progression. Dr. Reddy鈥檚 research dates back to 1997 when he began working with Dr. Craig Hartley in developing the first Doppler Flow Velocity signal acquisition and processing systems. Using the custom-built sensors and devices the laboratory adapted these measurement techniques from large animals and humans, using them to assess cardiovascular function in mice and other rodents. Over almost two decades Dr. Reddy鈥檚 research has included the use of Doppler Flow Velocity measurements (without image guidance) to measure cardiac velocities, blood flow velocities in central and peripheral vessels, coronary flow velocity, stenotic jet velocity, arterial pulse-wave velocity, tail-cuff blood pressure, arterial wall motion, and tissue Doppler. Imaging methods are used when cardiac and vascular dimensions are required, while invasive methods are used mainly to measure aortic, arterial, and left ventricular pressure. Efforts are underway to develop non-invasive indices of aortic impedance and LV systemic load using aortic wall motion and velocity measurements and more recently we have found indications that peak aortic blood acceleration correlates well with left ventricular dp/dtmax potentially removing the need for this invasive measurement as well.
Websites
Selected Publications
- Moudgil R, Samra G, Ko KA, Vu HT, Thomas TN, Luo W, Chang J, Reddy AK, Fujiwara K, Abe J-I "." Front Cardiovasc Med. 2020 Nov;7:594123. doi: 10.3389/fcvm.2020.594123. Pubmed PMID:
- Cieslik KA, Sekhar RV, Granillo A, Reddy AK, Medrano G, Heredia CP, Entman ML, Hamilton DJ, Li S, Reineke E, Gupte AA, Zhang A, Taffet GE. "." J Gerontol - A Biol Sci Med Sci. 2018;73(9):1167-1177. Pubmed PMID:
- Kho J, Tian X, Wong WT, Bertin T, Jiang MM, Chen S, Jin Z, Shchelochkov OA, Burrage LC, Reddy AK, Jiang H, Abo-Zahrah R, Ma S, Zhang P, Bissig KD, Kim JJ, Devaraj S, Rodney GG, Erez A, Bryan NS, Nagamani SCS, Lee BH. "." Am J Human Genet. 2018;103(2):276-287. Pubmed PMID:
- Salazar BH, Hoffman KA, Reddy AK, Madala S, Birla RK. "." Cardiovasc Engineer Technol. 2018;9(1):94-104. Pubmed PMID:
- Salazar BH, Hoffman KA, Reddy AK, Madala S, Birla RK. "Noninvasive measurement of EKG properties of 3D artificial heart muscle.." AIMS Cell Tiss Engineer. 2017;1(1):12-30.
- Zhou H, Ran Y, Da Q, Shaw TS, Shang D, Reddy AK, L贸pez JA, Ballantyne CM, Ware J, Wu H, Peng Y. "." J Immunol. 2016;197:288-295. Pubmed PMID:
- Medrano G, Hermosillo-Rodriguez J, Pham T, Granillo A, Hartley CJ, Reddy AK, Osuna PM, Entman ML, Taffet GE. "." J Gerontol - A Biol Sci Med Sci. 2016;71(9):1141-1150. Pubmed PMID:
- Hinton AO Jr, Yang Y, Quick AP, Xu P, Reddy CL, Yan X, Reynolds CL, Tong Q, Zhu L, Xu J, Wehrens XH, Xu Y, Reddy AK "." PLoS One. 2016;11(12):e0168644. doi: 10.1371/journal.pone.0168644.. Pubmed PMID:
- Salazar B, Reddy AK, Tao Z, Madala S, Birla R. "." IEEE Trans Biomed Engineer. 2015;62(6):1614-1622. Pubmed PMID:
- Grimes KM*, Reddy AK*, Lindsey ML, Buffenstein R. "." Am J Physiol Heart and Circ Physiol. 2014;307:H284-H291.. Pubmed PMID:
- Reddy AK, Hartley CJ, Thuy T. Pham, Darlington G, Entman ML, Taffet GE. "." J Gerontol - A Biol Sci Med Sci. 2014;69:152-159. Pubmed PMID:
- Gurha P, Wang T, Larimore AH, Sassi Y, Abreu-Goodger C, Ramirez MO, Reddy AK, Engelhardt S, Taffet GE, Wehrens XH, Entman ML, Rodriguez A. "." PLoS One. 2013;8(9):e75882. Pubmed PMID:
- Crossland RF, Durgan DJ, Lloyd EE, Phillips SC, Reddy AK, Marrelli SP, Bryan RM Jr. "." Am J Physiol Regul Integ Comp Physiol. 2013;305:R334-R342. Pubmed PMID:
- Christia P, Bujak M, Gonzalez-Quesada C, Chen W, Dobaczewski M, Reddy AK, Frangogiannis NG "." J Histochem Cytochem. 2013;61(8):555-570. Pubmed PMID:
- Gurha P, Abreu-Goodger C, Wang T, Ramirez MO, Drumond AL, van Dongen S, Chen Y, Bartonicek N, Enright AJ, Lee B, Kelm RJ, Reddy AK, Taffet GE, Bradley A, Wehrens XH, Entman ML, Rodriguez A "." Circulation. 2012 Jun 5;125(22):2751-61. Pubmed PMID:
- Nagamani SC, Campeau PM, Shchelochkov OA, Premkumar MH, Guse K, Brunetti-Pierri N, Chen Y, Sun Q, Tang Y, Palmer D, Reddy AK, Li L, Slesnick TC, Feig DI, Caudle S, Harrison D, Salviati L, Marini JC, Bryan NS, Erez A, Lee B "." Am. J. Hum. Genet.. 2012 May 4;90(5):836-46. Pubmed PMID:
- Lloyd EE, Crossland RF, Phillips SC, Marrelli SP, Reddy AK, Taffet GE, Hartley CJ, Bryan RM "." Hypertension. 2011 Oct;58(4):672-8. Pubmed PMID:
- Hartley CJ, Reddy AK, Madala S, Entman ML, Michael LH, Taffet GE "." Am. J. Physiol. Heart Circ. Physiol.. 2011 Aug;301(2):H269-78. Pubmed PMID:
- Erez A, Nagamani SC, Shchelochkov OA, Premkumar MH, Campeau PM, Chen Y, Garg HK, Li L, Mian A, Bertin TK, Black JO, Zeng H, Tang Y, Reddy AK, Summar M, O'Brien WE, Harrison DG, Mitch WE, Marini JC, Aschner JL, Bryan NS, Lee B "." Nat. Med.. 2011;17(12):1619-26. Pubmed PMID:
- Hartley CJ, Reddy AK, Madala S, Entman ML, Taffet GE "." Ultrasound Med Biol. 2010 Jul;36(7):1169-75. Pubmed PMID:
- Tovar Perez JE, Heredia CP, Pham TT, Madala S, Hartley CJ, Entman ML, Taffet GE, Reddy AK "." Scientific Rep. 2021;11:536;doi: 10.1038/s41598-020-79866-y. Pubmed PMID:
Memberships
- American Heart Association
- Professional Member (01/2005)
- American Association for Laboratory Animal Science
- Member (08/2013)
to edit your profile