Dr. Orengo serves as a co-investigator in the Undiagnosed Diseases Network (UDN) at 7m视频. This NIH funded multi-site collaborative effort is designed to use high level sequencing, transcriptomics metabolomics and animal modeling resources to solve tough cases of undiagnosed individuals with rare diseases. .
All members of the Orengo lab are required to keep an electronic lab notebook via the Benchling interface. .
An integral part of the Orengo lab is integrating a cross species approach towards understanding motor neuron biology and disease: Human, Mouse and Zebrafish. The following links are frequently used by lab members in their day-to-day research and serve as great resources.
The Zebrafish Information Network (ZFIN) is the database of genetic and genomic data for the zebrafish (Danio rerio) as a model organism. ZFIN provides a wide array of expertly curated, organized and cross-referenced zebrafish research data.
The Genome Aggregation Database (gnomAD) is a resource developed by an international coalition of investigators, with the goal of aggregating and harmonizing both exome and genome sequencing data from a wide variety of large-scale sequencing projects, and making summary data available for the wider scientific community.
Search for genes or proteins and their functional terms extracted and organized from over a hundred publicly available resources.
A suite of gene list enrichment analysis tools.
The Allen Institute for Brain Science uses a unique approach to generate data, tools and knowledge for researchers to explore the biological complexity of the mammalian brain. This portal provides access to high quality data and web-based applications created for the benefit of the global research community.
